… allergen exposure to damaged skin in mice, as can occur in … and thereby prevent
FcϵRI-mediated mast cell activation. … that two independent strains of mice lacking mast cells, Kit W-…

… reduced allergen-specific responses in a peanut allergy mouse … actin fibers that inhibit
FcϵRI-mediated calcium flux and … disease-modifying allergen-independent therapies available in …

… the peanut allergen rather than the canonical allergen itself … inhibition of Fas/FasL-independent
apoptosis, and increased … expression in mouse bone marrow–derived mast cells (BMMCs…

… that causes IgE-independent mast cell activation. The receptor … growth factor for both mouse
and human mast cells. It has … high-affinity IgE receptor FcεRI-mediated signaling, resulting in …

… , mice that have large numbers of activated hu mast cells. … ; an IgE-independent decrease
in mast cell responsiveness (… mechanisms involved in FcεRI-mediated mast cell activation and …

… -mediated anaphylaxis in mice through mast cell inhibition. … achieved in an allergen-independent
manner with bispecific … for other Siglecs that inhibit FcϵRI-mediated signaling such as …

… in sensitized mice could be activated by the allergen via the … repeated allergen exposure,
which likely occurs in allergen-… flatten and spread upon FcεRI-mediated activation for increased …

… on IgE-independent mast cell activation, particularly via Mrgprb2 (mouse) and MRGPRX2
(… miR-155 plays a critical role in FcεRI-mediated MC responses by modulating components of …

… 4 food allergy and mouse models of colitis, arthritis, and … shown), did not induce spontaneous
mast cell degranulation (… 3 independent experiments performed with mouse or human …

… EP2 and EP4 agonism also curbed FcεRI-mediated … be influenced by factors independent
of the eliciting allergen that modulate … in 2 mouse strains commonly used as models of allergic …